发明名称 BICYCLIC COMPOUNDS HAVING BRADYKININ RECEPTORS AFFINITY AND PHARMACEUTICAL COMPOSITIONS THEREOF
摘要 Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
申请公布号 CA2521937(A1) 申请公布日期 2004.10.28
申请号 CA20042521937 申请日期 2004.04.12
申请人 AMGEN INC.;ARRAY BIOPHARMA, INC. 发明人 NOMAK, RANA;GRONEBERG, ROBERT D.;ASKEW, BEN;CHEN, JIAN J.;MARESKA, DAVID A.;D'AMICO, DERIN C.;ZHAN, JAMES;HARRIED, SCOTT;BISWAS, KAUSTAV;LIU, QINGYAIN;KIM, YONGBOO;RIAHI, BABAK;YANG, KEVIN;LI, AIWEN;YUAN, CHESTER CHENGUANG;QIAN, WENYUAN;FOTSCH, CHRISTOPHER H.;HAN, NIANHE;TORO, ANDRAS
分类号 A61K31/18;A61K31/277;A61K31/405;A61K31/47;A61P25/04;A61P29/00;C07C311/19;C07C311/29;C07D205/04;C07D207/12;C07D207/16;C07D207/20;C07D209/14;C07D209/16;C07D209/40;C07D209/52;C07D211/38;C07D211/44;C07D211/46;C07D211/60;C07D211/70;C07D213/42;C07D213/56;C07D213/64;C07D215/38;C07D215/40;C07D215/42;C07D217/22;C07D233/54;C07D239/74;C07D271/08;C07D277/64;C07D279/02;C07D285/14;C07D295/125;C07D295/13;C07D295/135;C07D307/14;C07D307/28;C07D307/79;C07D307/81;C07D311/68;C07D317/58;C07D333/20;C07D333/24;C07D333/58;C07D333/62;C07D405/04;C07D405/06;C07D405/12;C07D407/06;C07D407/12;C07D409/06;C07D409/12;C07D413/12;C07D417/12;C07D471/04;C07D487/08;(IPC1-7):C07C311/18;C07D279/00;A61K31/33;A61K31/34 主分类号 A61K31/18
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