HIGH CONCENTRATION ANTIBODY AND PROTEIN FORMULATIONS

摘要

The present application relates to highly concentrated antibody and protein formulations with reduced viscosity that are stable, relatively isotonic and are of low turbidity. The formulations are particularly suitable for subcutaneous administration. The application further describes articles of manufacture containing such formulations and method for using them to treat disorders treatable by the formulated antibody or protein. The formulations comprise arginine-HC1, histidine and polysorbate.