| 摘要 |
<p>Porous articles (A) having an antibiotic coating, where a coating of a salt (I) of fusidic acid (FA) with antibiotic (AB) is applied to the pore system of a non-metallic and/or metallic article, (I) being sparingly soluble in water or aqueous media and AB being gentamicin, sisomycin, netilmycin, streptomycin, tobramycin, spectinomycin, vancomycin, ciprofloxacin, moxifloxacin, clindamycin, lincomycin, tetracycline, chlorotetracycline, oxytetracycline or rolitetracycline. An independent claim is also included for the preparation of (A), by applying an aqueous solution of soluble salt(s) of AB to the pore system of the porous articles, then applying an aqueous solution of a sparingly soluble salt of FA to form (I) in the pore system; alternatively the order of the steps may be reversed.</p> |
