摘要 |
<p>5'-acyloxynucleoside compound is prepared by subjecting 2',3',5'-triacyloxynucleoside compound to selective deacylation in alcohol using base consisting of alkali metal hydroxide, alkali metal alkoxide, or alkali metal carbonate. [Image] R1>acyl; R2>, R3>acyl; R4>compound of formula (1) or (2); R5>hydrocarbon, alkoxy, or optionally substituted aryloxy; X : H, halo, amino, alkyl, aralkyl, substituted amino or hydroxyl;and Y : H, halo, alkyl, aralkyl, or aryl. [Image].</p> |