COMBINATION OF A RETINOIC ACID METABOLISM BLOCKING AGENT AND A TOCOPHEREOL
摘要
The present invention is concerned with the use of a tocopherol for the manufacture of a medicament for avoiding, alleviating, suppressing or overcoming the adverse side-effects of therapy with a retinoic acid metabolism blocking agent. The present invention is also concerned with the combination of 4-(heteroaryl-methyl)anilines with vitamin E and its use as a medicine.
申请公布号
EP1037629(B1)
申请公布日期
2004.10.27
申请号
EP19980966615
申请日期
1998.12.12
申请人
JANSSEN PHARMACEUTICA N.V.
发明人
DE PORRE, PETER, MARIE-ZOE, ROBERT;BRUYNSEELS, JAN, PAUL, JOZEF, MICHEL;WOUTERS, WALTER, BOUDEWIJN, LEOPOLD