发明名称 COMBINATION OF A RETINOIC ACID METABOLISM BLOCKING AGENT AND A TOCOPHEREOL
摘要 The present invention is concerned with the use of a tocopherol for the manufacture of a medicament for avoiding, alleviating, suppressing or overcoming the adverse side-effects of therapy with a retinoic acid metabolism blocking agent. The present invention is also concerned with the combination of 4-(heteroaryl-methyl)anilines with vitamin E and its use as a medicine.
申请公布号 EP1037629(B1) 申请公布日期 2004.10.27
申请号 EP19980966615 申请日期 1998.12.12
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 DE PORRE, PETER, MARIE-ZOE, ROBERT;BRUYNSEELS, JAN, PAUL, JOZEF, MICHEL;WOUTERS, WALTER, BOUDEWIJN, LEOPOLD
分类号 C07D413/12;A61K31/00;A61K31/355;A61K31/395;A61K31/423;A61K31/428;A61K45/00;A61P17/06;A61P35/00;A61P39/00;A61P43/00;C07D417/12;(IPC1-7):A61K31/395 主分类号 C07D413/12
代理机构 代理人
主权项
地址