发明名称 4-aminobenzopyran derivatives
摘要 This invention relates to benzopyran derivatives of the formula (I) wherein, R<1 >and R<2 >represent each independently a C1-6alkyl group, etc, R<3 >represents a hydroxyl group, etc, R<4 >represents a hydrogen atom, etc, R<6 >represents a hydrogen atom, R<7 >represents a hydrogen atom, etc, X is absent, or represents C=O, etc, R<8 >represents a hydrogen atom, a C1-6alkyl group, etc, R<9 >represents a hydrogen atom or a nitro group, when R<9 >represents a nitro group, Y represents a C4-8alkylene group, -(CH2)m-CR<11>R<12>-(CH2)n- or -(CH2)o-O-(CH2)p-, R<5 >represents a hydrogen atom, an amino group, a C1-6alkoxy group, a C1-6alkylthio group, a C1-6alkylamino group, a C1-6 alkoxycarbonylamino group, etc, or pharmaceutically acceptable salts thereof. These compounds are useful as an antiarrhythmic agent.
申请公布号 US6809114(B2) 申请公布日期 2004.10.26
申请号 US20030466175 申请日期 2003.07.14
申请人 NISSAN CHEMICAL INDUSTRIES, LTD. 发明人 OHARA YOSHIO;OHRAI KAZUHIKO;YANAGIHARA KAZUFUMI;SHIGETA YUKIHIRO;TSUKAGOSHI TORU;YAMASHITA TORU
分类号 A61P9/00;C07D311/70;C07D311/72;(IPC1-7):A61K31/335 主分类号 A61P9/00
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