发明名称 |
USO DI DERIVATI DEL 7-NITRO-2, 1, 3-BENZOSSADIAZOLO PER |
摘要 |
Derivatives of the heterocyclic compound known as 7-nitro-benzofurazan or 7-nitro-2,1,3-benzoxadiazole, are agents having a strong inhibiting activity towards members of the glutathione S-transferase (GST) superfamily that are hyperexpressed in cancer cells, and make them particularly resistant to many stress factors. These compounds are useful in the production of pharmaceutical drugs to be used in anticancer therapy, and may be employed either alone or in combination with other chemotherapeutic agents. |
申请公布号 |
ITRM20030194(A1) |
申请公布日期 |
2004.10.25 |
申请号 |
IT2003RM00194 |
申请日期 |
2003.04.24 |
申请人 |
UNIVERSITA' DEGLI STUDI DI ROMA TOR VERGATA |
发明人 |
CACCURI ANNA MARIA;RICCI GIORGIO |
分类号 |
A61K;A61K31/4245;A61K45/06;A61P35/00 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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