发明名称 |
Using polynucleotide probes based on the FANCC gene (Fanconi anemia, complementation group C), for diagnosis of psoriasis, or predisposition, and in screening for antipsoriatic agents |
摘要 |
<p>Use of a polynucleotide probe (A) of 10-500 bp and at least 80% complementary with a target corresponding to all or part of the FANCC (Fanconi anemia, complementation group C) gene (NM 000136.1) (a) for characterizing a biological sample by measuring the level of FANCC or (b) for identifying compounds (I) for treatment of psoriasis. Independent claims are also included for the following: (1) method for identifying (I); (2) research tool or diagnostic kit that comprises (A); (3) method for diagnosing psoriasis, or a predisposition to it, by measuring overexpression of FANCC, by contacting a test sample with (A). ACTIVITY : Antipsoriatic. No details of tests for antipsoriatic activity are given. MECHANISM OF ACTION : RNAi; RNA interference; Antisense oligonucleotide inhibitor.</p> |
申请公布号 |
FR2853910(A1) |
申请公布日期 |
2004.10.22 |
申请号 |
FR20030004773 |
申请日期 |
2003.04.16 |
申请人 |
GALDERMA RESEARCH & DEVELOPMENT |
发明人 |
TRINQUET VALERIE;ROSSIO PATRICIA;FOGEL PAUL |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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