MEDICINAL COMPOSITION CONTAINING PYRROLOPYRIDAZINE DERIVATIVE

摘要

A medicinal composition which comprises a pyrropyridazine compound having a structure represented by the general formula (I): (I) (wherein R<1> is alkenyl, halogenoalkenyl, alkynyl, cycloalkyl, or optionally substituted cycloalkylalkyl; R<2> is hydrogen or alkyl; R<3> is hydrogen, alkyl, or hydroxyalkyl; R<4> is hydrogen or alkyl; R<5> is optionally substituted phenyl; A is alkylene; and X is oxygen or sulfur) or the like and an antibacterial effective against Helicobacter pylori. The medicinal composition is used in such a manner that the two components are administered simultaneously or separately at an interval. The medicinal composition is highly effective in removing Helicobacter pylori from a person infected with Helicobacter pylori. It is hence useful as a medicinal composition for warm-blooded animals.