发明名称 Vascularization inhibitors
摘要 This invention provides a therapeutic agent for inhibiting neovascularization, a therapeutic agent for a solid cancer, a therapeutic agent for a disease pathologically caused by neovascularization, and a therapeutic agent for repairing a tissue comprising as the effective ingredient, a substance that potentiates the action of CXCR4. Based on the finding that vascularization is suppressed in CXCR4 knockout mice, it becomes possible to prepare a therapeutic agent for suppressing vascularization, a therapeutic agent for a solid cancer, a therapeutic agent for a disease pathologically caused by neovascularization, each of which comprises as the effective ingredient, a substance that inhibits the action of CXCR4, as well as to prepare a therapeutic agent for repairing a tissue comprising as the effective ingredient, a substance that potentiates the action of CXCR4. Methods for treatment are made possible that use these therapeutic agents.
申请公布号 US2004209837(A1) 申请公布日期 2004.10.21
申请号 US20040785230 申请日期 2004.02.25
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 KISHIMOTO TADAMITSU;NAGASAWA TAKASHI;TACHIBANA KAZUNOBU
分类号 A61K38/17;(IPC1-7):A61K48/00 主分类号 A61K38/17
代理机构 代理人
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