发明名称 Targeted MHC class I alpha3 vaccine delivery systems
摘要 The present invention is directed to a novel targeted vaccine delivery system, comprising one or more isolated MHC class I alpha3 domains linked to an antibody which is specific for a cell surface marker and associated with beta2-microglobulin and antigenic peptides, or costimulatory molecules, or cytokines. The complexes of the invention are useful for treating and/or preventing cancer, infectious diseases, autoimmune diseases, and/or allergies.
申请公布号 US2004210037(A1) 申请公布日期 2004.10.21
申请号 US20040809790 申请日期 2004.03.26
申请人 VACCINEX INC 发明人 ZAUDERER MAURICE;PARIS MARK J;SMITH ERNEST S
分类号 A61K;A61K38/00;A61K39/00;A61K39/145;A61K39/25;A61K39/38;A61K39/40;C07K14/045;C07K14/74;C07K16/28;C07K16/46;C12P21/08;(IPC1-7):C07K16/46 主分类号 A61K
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