发明名称 |
ACYL- PHOSPHATE AND PHOSPHONATE PROBES AND METHODS OF THEIR SYNTHESIS AND USE IN PROTEOMIC ANALYSIS |
摘要 |
The present invention provides tagged acyl phosphate probes ("TAPPs"), and methods of their preparation and use. The subject methods and compositions c an provide enhanced simplicity and accuracy in identifying changes in the presence, amount, or activity of target proteins in a complex protein mixtur e, preferably nucleotide binding proteins using nucleotide binding protein- directed TAPPs. The profiling methods described herein can have a number of steps leading to the identification of target nucleotide binding protein(s) in a complex protein mixture.
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申请公布号 |
CA2521130(A1) |
申请公布日期 |
2004.10.21 |
申请号 |
CA20042521130 |
申请日期 |
2004.04.01 |
申请人 |
ACTIVX BIOSCIENCES, INC. |
发明人 |
CAMPBELL, DAVID ALAN;WU, MIN;SZARDENINGS, ANNA KATRIN;LIYANAGE, MAREK |
分类号 |
C07F9/6512;C07H19/10;C07H19/20;C07H21/04;C07K9/00;C12Q;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C07F9/6512 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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