发明名称 Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto
摘要 3-Deoxyflavonoid compounds and methods for inhibiting T-cell activity and treating diseases and disorders (e.g., autoimmune disorders, inflammatory disorders, diabetes, ALS, MS, rheumatoid arthritis, etc.). In some cases the efficacy and/or duration of action of luteolin and/or other 3-dioxyflavinoid compounds may be increased by administering such compounds along with Rutin, a Rutin congener and/or a Rutin derivative. Also, in some cases, first pass metabolism of luteolin or other 3-deoxyflavinoids may be avoided by administering such compounds by parenteral routes (e.g., sublingual, buccal, intranasal, injection, etc.).
申请公布号 US2004209825(A1) 申请公布日期 2004.10.21
申请号 US20040838766 申请日期 2004.05.04
申请人 LAHEY THOMAS P.;RAJADHYAKSHA V.J. 发明人 LAHEY THOMAS P.;RAJADHYAKSHA V.J.
分类号 A61K31/352;A61K31/353;A61K31/36;A61K31/661;A61K31/7048;A61P3/10;A61P21/00;A61P37/06;C07D311/30;C07D311/32;C07D311/36;C07D407/04;C07D493/04;C07F9/655;(IPC1-7):A61K31/704;C07H17/00 主分类号 A61K31/352
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