| 摘要 |
There is disclosed an advantageous mixed acid anhydride production method of formula (1): R<1>C(O)OY(O)n(R<2>)p (1) wherein R<1>, R<2 >and Y denote the same as defined below, n and p denote an integer of 1 or 2, which is characterized by adding a carboxylic acid of formula (2); R<1>COOH (2) wherein R<1 >denotes a hydrogen atom, an optionally substituted alkyl group or the like, an organic base to a solution of a carboxylic acid activating agent of formula (3); (R<2>)pY(O)nX (3) wherein R<2 >denotes an optionally substituted aliphatic hydrocarbyl group or the like, Y denotes a carbon atom, a phosphorus atom, or a sulfur atom, and X denotes a chlorine atom or the like.
|
