发明名称 Neutrokine-alpha conjugate, neutrokine-alpha complex, and uses thereof
摘要 The present invention is directed to a Neutrokine-alpha conjugate, wherein said Neutrokine-alpha conjugate comprises a Neutrokine-alpha protein and a chelator. The present invention is also directed to a Neutrokine-alpha complex, wherein said Neutrokine-alpha complex comprises a Neutrokine-alpha conjugate and a metal ion wherein said metal ion is noncovalently associated with the chelator of said conjugate. The present invention is further directed to compositions, specifically pharmaceutical and diagnostic compositions, comprising a Neutrokine-alpha conjugate or complex as described herein. Therapeutic and diagnostic uses of said conjugate, complex, and compositions are described.
申请公布号 US2004208824(A1) 申请公布日期 2004.10.21
申请号 US20030742634 申请日期 2003.12.22
申请人 PARMELEE DAVID;YEH REN-HWA;GALPERINA OLGA;HILBERT DAVID;ROSEN CRAIG A. 发明人 PARMELEE DAVID;YEH REN-HWA;GALPERINA OLGA;HILBERT DAVID;ROSEN CRAIG A.
分类号 A61K47/48;C07K14/52;(IPC1-7):A61K49/00;C07K14/525 主分类号 A61K47/48
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