发明名称 |
Methods of improving health-related quality of life in individuals with systemic lupus erythematosus |
摘要 |
The invention provides methods for stabilizing or improving the health-related quality of life in individuals with SLE, and methods of selecting individuals suitable for such treatment. One method of stabilizing or improving the health-related quality of life of an individual with SLE involves the administration of an effective amount of dsDNA epitope, such as in the form of an epitope-presenting carrier or an epitope-presenting valency platform molecule like LJP 394, to the individual. The invention further provides a method of stabilizing or improving the health-related quality of life of an individual with SLE involving the reduction of the level of SLE-associated antibodies in the individual, optionally through administration of a dsDNA epitope to the individual. In addition, methods of screening patients are provided. Kits useful in the methods of the invention are also provided.
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申请公布号 |
US2004208864(A1) |
申请公布日期 |
2004.10.21 |
申请号 |
US20030748541 |
申请日期 |
2003.12.29 |
申请人 |
STRAND VIBEKE;LINNIK MATTHEW D.;JOH TENSHANG |
发明人 |
STRAND VIBEKE;LINNIK MATTHEW D.;JOH TENSHANG |
分类号 |
A61K31/70;A61K39/395;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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