发明名称 METHODS FOR IDENTIFYING COMBINATIONS OF ENTITIES AS THERAPEUTICS.
摘要 The invention features a method of screening two-entity or higher order combinations for biological activity using combinational arrays. The method includes the steps of: (a) providing the entities, (b) creating an array of combinations of entities, (c) providing a test element that includes one or more distinct biological moieties, (d) contacting the array of combinations of entities with the test element under conditions that ensure that each entity/test element contacting is segregated from the others, (e) detecting or measuring a property of the test element, and (f) identifying combinations of entities that cause an effect on the property of the test element that is different from the effect of an entity of the combination by itself.
申请公布号 MXPA01006914(A) 申请公布日期 2004.10.15
申请号 MX2001PA06914 申请日期 2001.07.06
申请人 COMBINATORX, INCORPORATED. 发明人 MICHAEL A. FOLEY.
分类号 G01N21/64;A61K45/00;A61P35/00;C12Q1/20;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/58;G01N37/00;(IPC1-7):G01N33/50;G01N33/543 主分类号 G01N21/64
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