发明名称 |
VERFAHREN UND ZUSAMMENSETZUNGENFÜR DIE SYNTHESE VON LANGKETTIGEN, MEHRFACH UNGESÄTTIGTEN FETTSÄUREN |
摘要 |
The present invention relates to a fatty acid DELTA5-desaturase able to catalyze the conversion of dihomo-gamma-linolenic acid to arachidonic acid. Nucleic acid sequences encoding a DELTA5-desaturase, nucleic acid sequences which hybridize thereto, DNA constructs comprising a DELTA5-desaturase gene, and recombinant host microorganism or animal expressing increased levels of a DELTA5-desaturase are described. Methods for desaturating a fatty acid at the DELTA5 position and for producing arachidonic acid by expressing increased levels of a DELTA5 desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a DELTA5-desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a DELTA5-desaturase produced by a recombinant host microorganism or animal also are described. |
申请公布号 |
AT277188(T) |
申请公布日期 |
2004.10.15 |
申请号 |
AT19980918175T |
申请日期 |
1998.04.10 |
申请人 |
CALGENE LLC;ABBOTT LABORATORIES |
发明人 |
KNUTZON, DEBORAH;MUKERJI, PRADIP;HUANG, YUNG-SHENG;THURMOND, JENNIFER;CHAUDHARY, SUNITA;LEONARD, AMANDA, EUN-YEONG |
分类号 |
A23D9/00;A23K1/00;A23K1/16;A23L1/29;A23L1/30;A61K31/20;A61K31/202;A61K38/00;A61P3/02;C11B1/00;C11C3/00;C12N1/19;C12N5/10;C12N9/02;C12N15/09;C12N15/53;C12N15/81;C12N15/82;C12N15/83;C12P7/64;C12Q1/68 |
主分类号 |
A23D9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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