| 发明名称 |
THROMBIN INHIBITORS PRECURSORS, AS METHOD FOR THE THROMBIN INHIBITORS PRECURSORS, AS METHOD FOR THE PREPARATION THEREOF, A PHARMACEUTICAL COMPOSITION PREPARATION THEREOF, A PHARMACEUTICAL COMPOSITION BASED THEREON AND A METHOD FOR THE TREATMENT BASED THEREON AND A METHOD FOR THE TREATMENT |
| 摘要 |
There is provided compounds of formula (I): R1O(O)C-CH2(R)Cgl-Aze-Pab-R2, wherein R1 and R2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants. |
| 申请公布号 |
UA70280(C2) |
申请公布日期 |
2004.10.15 |
| 申请号 |
UA19980052780 |
申请日期 |
1996.12.17 |
| 申请人 |
ASTRAZENECA AB ASTRAZENECA AB |
发明人 |
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| 分类号 |
C12N9/99;A61K;A61K38/55;A61P7/02;A61P9/10;A61P43/00;C07K;C07K1/02;C07K5/00;C07K5/06;C07K5/065;(IPC1-7):C07K5/00 |
主分类号 |
C12N9/99 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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