发明名称 COMBINATION OF FENOFIBRATE AND COENZYME Q10 FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION.
摘要 <p>The present invention relates to a combination of a peroxisome proliferator activated receptor (PPAR) activator and a benzoquinone and their use in treating and/or preventing disorders characterized by endothelial dysfunction, such as cardiovascular disease, strokes and myocardial infarction. According to a preferred embodiment of the invention the benzoquinone or precursor thereof is a ubiquinone or precursor thereof, more preferably, coenzyme Q10 or a precursor thereof, and the PPAR activator is a fibrate or a thiazolidinedione, more preferably fenofibrate.</p>
申请公布号 MXPA03003733(A) 申请公布日期 2004.10.15
申请号 MX2003PA03733 申请日期 2001.10.23
申请人 FOURNIER LABORATORIES IRELAND LIMITED 发明人 PLAYFORD, DAVID
分类号 A61K47/20;A61K31/12;A61K31/122;A61K31/215;A61K31/216;A61K45/00;A61P3/06;A61P3/10;A61P7/08;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P9/14;A61P39/06;A61P43/00;(IPC1-7):A61K31/12 主分类号 A61K47/20
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