发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING PROTEINS MODIFIED INPRECONDITIONING AGAINST ISCHEMIA/HYPOXIA |
摘要 |
Proteins modified by pharmacological preconditioning are provided. Compositions, methods and events for modulating these proteins and priming cells for preconditioning and inducing preconditioning in a cell, tissue or organ as well as methods for identifying new compositions and methods for such priming and induction are also provided. In addition, methods for diagnosing and monitoring preconditioning or ischemic, hypoxic, ischemic/reperfusion and hypoxic/reperfusion conditions or the ability of a cell, tissue or organ to survive injury by measuring modulation of one or more of these preconditioning proteins are provided.
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申请公布号 |
CA2464175(A1) |
申请公布日期 |
2004.10.14 |
申请号 |
CA20042464175 |
申请日期 |
2004.04.14 |
申请人 |
QUEEN'S UNIVERSITY AT KINGSTON |
发明人 |
ARRELL, D. KENT;VAN EYK, JENNIFER E.;ELLIOTT, STEVEN T. |
分类号 |
A61K31/5415;A61K31/7076;A61K38/44;A61K38/46;A61K45/00;C12Q1/02;G01N33/50;(IPC1-7):A61K31/707;A61K31/541 |
主分类号 |
A61K31/5415 |
代理机构 |
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代理人 |
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地址 |
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