发明名称 |
Cis-element decoys useful as anti-tumor therapeutics |
摘要 |
An anti-cancer or oncogene switching therapeutics that employ sequence-specific nucleic acid decoys for competitive binding of transcription factors. These nucleic acid decoys can competitively bind to transcription factors regulating the expression of oncogenes including CREB, JUN/FOS, JUN/ATF and MYC/MAX in the cell, leading to the inhibition of tumor cell growth. As a result, they can be developed into anti-cancer therapeutic drugs.
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申请公布号 |
US2004204374(A1) |
申请公布日期 |
2004.10.14 |
申请号 |
US20030411692 |
申请日期 |
2003.04.11 |
申请人 |
WANG XUEGEN;YE QING;CHEN WULING;FENG YING |
发明人 |
WANG XUEGEN;YE QING;CHEN WULING;FENG YING |
分类号 |
A61K48/00;C07H21/04;(IPC1-7):A61K48/00 |
主分类号 |
A61K48/00 |
代理机构 |
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