发明名称 Process for preparation of erythromycin compounds
摘要 The present invention is to provide a process for producing a 2'-O-acetyl-4''-O-formyl-8,9-anhydroerythromycin A 6,9-hemiketal compound 4, and it provide a process for producing an erythromycin compound which comprises reacting a formylating agent with a 2'-O-acetylerythromycin A compound 2 to obtain 2'-O-acetyl-4''-O-formylerythromycin A compound 3, then, acting an acid on Compound 3 to subject to hemiketalation, and then adding an aqueous basic solution in an aqueous solution to precipitate Compound 4 as free crystals.
申请公布号 US2004204573(A1) 申请公布日期 2004.10.14
申请号 US20030480275 申请日期 2003.12.11
申请人 MIYATA HIROYUKI;TAKAMA AKIRA;YAMAMOTO YASUHITO;ATAKA KIKUO 发明人 MIYATA HIROYUKI;TAKAMA AKIRA;YAMAMOTO YASUHITO;ATAKA KIKUO
分类号 C07H17/08;(IPC1-7):C07H17/08 主分类号 C07H17/08
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