Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors

摘要

The present application describes lactam-containing cyclic diamines and derivatives thereof of Formula I: P4-M-M4 I or pharmaceutically acceptable salt forms thereof, wherein M is a non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.