发明名称 |
SELECTED RNA MOTIFS TO INCLUDE CELL DEATH AND/OR APOPTOSIS |
摘要 |
The present application is directed to the use of dsRNA and/or ssRNA for the purpose of inducing apoptosis or cell death in proliferating cells. Specifically, low molecular weight and high molecular weight dsRNA and ssRNA are shown to induce apoptosis and/or cell death in proliferating cells, to arrest proliferation of transformed cells or tumor cells and to cause rapid induction of the cytokine TNF-alpha and/or also induce production of IL-12 which directs a Th-1 response. |
申请公布号 |
WO2004087877(A2) |
申请公布日期 |
2004.10.14 |
申请号 |
WO2004US09261 |
申请日期 |
2004.03.25 |
申请人 |
ASTRAL INC.;SMITH, DAN;BOT, ADRIAN |
发明人 |
SMITH, DAN;BOT, ADRIAN |
分类号 |
A01N43/04;A61K31/07;C07H21/04;C12N;C12N15/117;C12Q1/68 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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