VERFAHREN ZUR HERSTELLUNG VON 1,8-DISUBSTITUIERTEN-1,3,4,9-TETRAHYDROPYRAN(3,4-B)-INDOL-1ESSIGSÄUREESTERN IN EINEM HYDROXYLHALTIGEN LÖSUNGSMITTEL

摘要

A process for the preparation of the esters of 1,8-disubstituted -1,3,4,9-tetrahydropyrano (3,4-b)-indole-1-acetic acid reacting 7-alkyltryptophol of Formula (II): with a beta -ketoester of formula (III), in a hydroxylic solvent, comprising at least one alkanol solvent having 1-4 carbon atoms, containing hydrogen chloride gas, and subsequently recovering the product of Formula (I) is delineated.