发明名称 FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF
摘要 <p>A fused heterocyclic derivative represented by the general formula (I) (wherein R&lt;1&gt; is hydrogen, OH, etc.; R&lt;2&gt; is hydrogen, halogeno, or alkyl; R&lt;3&gt; and R&lt;4&gt; each is hydrogen, OH, halogeno, etc.; Q is alkylene, etc.; ring A is aryl or heteroaryl; and G is the group represented by the formula (G1) or (G2)), (G1) (G2) a pharmacologically acceptable salt of the derivative, or a prodrug of either. They have excellent inhibitory activity against human SGLT and are useful as preventive or therapeutic agents for diseases attributable to hyperglycemia, such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, complications of diabetes, and obesity.</p>
申请公布号 WO2004087727(A1) 申请公布日期 2004.10.14
申请号 WO2004JP04009 申请日期 2004.03.24
申请人 KISSEI PHARMACEUTICAL CO., LTD.;FUSHIMI, NOBUHIKO;YONEKUBO, SHIGERU;MURANAKA, HIDEYUKI;SHIOHARA, HIROAKI;TERANISHI, HIROTAKA;SHIMIZU, KAZUO;ITO, FUMIAKI;ISAJI, MASAYUKI 发明人 FUSHIMI, NOBUHIKO;YONEKUBO, SHIGERU;MURANAKA, HIDEYUKI;SHIOHARA, HIROAKI;TERANISHI, HIROTAKA;SHIMIZU, KAZUO;ITO, FUMIAKI;ISAJI, MASAYUKI
分类号 A61K31/7036;A61K31/7042;A61K31/7048;A61K31/7056;A61K31/706;A61P3/04;A61P3/06;A61P3/10;A61P9/12;A61P7/10;A61P9/04;A61P9/10;A61P19/06;A61P43/00;C07H15/203;C07H17/00;C07H17/02;C07H17/04;(IPC1-7):C07H15/203;A61K31/703;A61K31/704;A61K31/705 主分类号 A61K31/7036
代理机构 代理人
主权项
地址