发明名称 Novel amide derivatives
摘要 This invention relates to compounds which are represented by the general formula [I] [in which A stands for a group of the following formula [ao] or [bo] Ar<1>, Ar<2 >and Ar<3 >stand for optionally substituted phenyl; k stands for 0 or 1; m, n and s stand for 0, 1 or 2; R<1 >stands for hydrogen or optionally substituted lower alkyl; R<2>, R<3>, R<4 >and R<5 >either stand for hydrogen or optionally substituted lower alkyl, or R<2 >and R<3>, or R<4 >and R<5 >together stand for trimethylene and the like; R<60 >stands for hydrogen, alkyl, or the like; R<61 >and R<71 >either stand for alkyl and the like, or together stand for trimethylene and the like; X stands for carbonyl or methylene; Y stands for nitrogen or methine; and Q<-> stands for anion], and the like. The compounds of the invention exhibit selective antagonism to muscarinic M3 receptors, and therefore are useful as safe and effective agents showing little side effect, for treating diseases of the respiratory, urinary and digestive systems.
申请公布号 US2004204369(A1) 申请公布日期 2004.10.14
申请号 US20040838340 申请日期 2004.05.05
申请人 SAGARA YUFU;UCHIYAMA MINAHO;NAYA AKIRA;KIMURA TOSHIFUMI;NUMAZAWA TOMOSHIGE;FUJIKAWA TORU;OTAKE NORIKAZU;NOGUCHI KAZUHITO 发明人 SAGARA YUFU;UCHIYAMA MINAHO;NAYA AKIRA;KIMURA TOSHIFUMI;NUMAZAWA TOMOSHIGE;FUJIKAWA TORU;OTAKE NORIKAZU;NOGUCHI KAZUHITO
分类号 A61P1/04;A61P1/06;A61P1/08;A61P11/00;A61P13/00;A61P43/00;C07D207/16;C07D211/26;C07D401/12;C07D401/14;C07D471/10;C07D493/10;C07D498/10;(IPC1-7):C07D211/26;A61K31/445 主分类号 A61P1/04
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