| 发明名称 |
CXCR4 ANTAGONISTS AND METHODS OF THEIR USE |
| 摘要 |
Compositions and methods for the treatment or prevention of a chemokine~ related or chemokine-receptor-related pathology are provided. In one aspect, the pathology is cancer. It has been discovered that CXCR4 antagonists, in particular CXCR4 peptide antagonists such as TN14003, inhibit or reduce tumo r metastasis in a host.
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| 申请公布号 |
CA2520406(A1) |
申请公布日期 |
2004.10.14 |
| 申请号 |
CA20042520406 |
申请日期 |
2004.03.26 |
| 申请人 |
EMORY UNIVERSITY |
发明人 |
LIANG, ZHONGXING;SHIM, HYUNSUK;GOODMANN, MARK;TAICHMAN, RUSSEL;UMBREIT, JAY |
| 分类号 |
A61K47/48;A61K;A61K6/00;A61K31/7105;A61K38/10;A61K47/22;A61P35/00;C12Q1/04;G01N21/64 |
主分类号 |
A61K47/48 |
| 代理机构 |
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代理人 |
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