发明名称 SELECTED RNA MOTIFS TO INCLUDE CELL DEATH AND/OR APOPTOSIS
摘要 The present application is directed to the use of dsRNA and/or ssRNA for the purpose of inducing apoptosis or cell death in proliferating cells. Specifically, low molecular weight and high molecular weight dsRNA and ssRNA are shown to induce apoptosis and/or cell death in proliferating cells, to arrest proliferation of transformed cells or tumor cells and to cause rapid induction of the cytokine TNF-alpha and/or also induce production of IL-12 which directs a Th-1 response.
申请公布号 CA2520181(A1) 申请公布日期 2004.10.14
申请号 CA20042520181 申请日期 2004.03.25
申请人 ASTRAL, INC. 发明人 BOT, ADRIAN;SMITH, DAN
分类号 A01N43/04;A61K31/07;C07H21/04;C12N;C12N15/117;C12Q1/68;(IPC1-7):C12Q1/68 主分类号 A01N43/04
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