摘要 |
The invention relates to pyrrolo pyrimidines of formula (I), wherein Y represents -(CH2)t-O- or -(CH2)r-S-, p is 1 or 2, r is 1, 2 or 3, t is 1, 2 or 3, or Y is -(CH2)j- or -CH=CH-, j is 1 or 2; p is 1 or 2, or Y is -(CH2)f-, f is 1 or 2, p is 1, and the further radicals and symbols have the meaning as defined herein; their preparation, their use as pharmaceuticals, pharmaceutical compositions containing them, the use of such a compound for the manufacture of a pharmaceutical preparation for the treatment of neuropathic pain and to a method for the treatment of such a disease in animals, especially in humans.
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申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH;BUXTON, FRANCIS, PAUL;EHARA, TAKERU;GANJU, PAMPOSH;HALLETT, ALLAN;IRIE, OZAMU;IWASAKI, ATSUKO;KANAZAWA, TAKANORI;MASUYA, KEIICHI;NONOMURA, KAZUHIKO;SAKAKI, JUNICHI;SNELL, CHRISTOPHER, ROBERT;SONG, CHUANHENG;TANABE, KEIKO;TENO, NAOKI;UMEMURA, ICHIRO;YOKOKAWA, FUMIAKI |
发明人 |
BUXTON, FRANCIS, PAUL;EHARA, TAKERU;GANJU, PAMPOSH;HALLETT, ALLAN;IRIE, OZAMU;IWASAKI, ATSUKO;KANAZAWA, TAKANORI;MASUYA, KEIICHI;NONOMURA, KAZUHIKO;SAKAKI, JUNICHI;SNELL, CHRISTOPHER, ROBERT;SONG, CHUANHENG;TANABE, KEIKO;TENO, NAOKI;UMEMURA, ICHIRO;YOKOKAWA, FUMIAKI |