<p>This invention relates to a compound which selectively inhibits PDE IV and wherein the IC50 value for the PDE IV catalytic form which binds rolipram with a high affinity is lower than the IC50 value for the form which binds rolipram with a low affinity and to uses thereof in therapy.</p>
申请公布号
EP1466598(A2)
申请公布日期
2004.10.13
申请号
EP20040076173
申请日期
1994.06.17
申请人
SMITHKLINE BEECHAM CORPORATION
发明人
BARNETTE, MARY S.;CHRISTENSEN, SIEGFRIED B., IV.;TORPHY, THEODORE J.