发明名称 PDE-IV inhibitors
摘要 <p>This invention relates to a compound which selectively inhibits PDE IV and wherein the IC50 value for the PDE IV catalytic form which binds rolipram with a high affinity is lower than the IC50 value for the form which binds rolipram with a low affinity and to uses thereof in therapy.</p>
申请公布号 EP1466598(A2) 申请公布日期 2004.10.13
申请号 EP20040076173 申请日期 1994.06.17
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 BARNETTE, MARY S.;CHRISTENSEN, SIEGFRIED B., IV.;TORPHY, THEODORE J.
分类号 A61K31/275;C07D487/04;A61K31/00;A61K31/277;A61K31/40;A61K31/47;A61K31/485;A61K31/505;A61K45/00;A61P11/08;A61P29/00;A61P43/00;C07C233/56;C07C255/46;C07D207/12;(IPC1-7):A61K31/275 主分类号 A61K31/275
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