发明名称 INHIBITORS OF DIPEPTIDYL PEPTIDASE IV
摘要 <p>Compounds according to formula (1), wherein R<SUP>1 </SUP>is H or CN, X<SUP>1 </SUP>is S, O, SO<SUB>2 </SUB>or CH<SUB>2</SUB>, X<SUP>2 </SUP>is CO, CH<SUB>2 </SUB>or a covalent bond, Het is a nitrogen-containing heterocycle and n is 1-5 are new. The compounds of the invention are inhibitors of dipeptidyl peptidase IV. Pharmaceutical compositions of the compounds of the invention, or pharmaceutically acceptable salts thereof, are useful in the treatment of, inter alia, type 2 diabetes</p>
申请公布号 EP1280797(B1) 申请公布日期 2004.10.13
申请号 EP20010923854 申请日期 2001.04.26
申请人 FERRING B.V. 发明人 EVANS, DAVID MICHAEL;PITT, GARY ROBERT WILLIAM
分类号 C07D277/20;A61K31/422;A61K31/427;A61K31/44;A61K31/4439;A61K31/47;A61K31/4709;A61K31/4725;A61K31/495;A61K31/497;A61K31/498;A61K31/506;A61P3/00;A61P3/10;A61P5/02;A61P5/06;A61P15/08;A61P29/00;A61P37/02;A61P43/00;C07D213/82;C07D241/24;C07D277/56;C07D401/12;C07D403/12;C07D413/12;C07D417/12;(IPC1-7):C07D403/12 主分类号 C07D277/20
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