Tricyclic lactam and sultam derivatives and their use as histone deacetylase inhibitors.
摘要
A compound of formula (I) wherein A and B are optionally substituted cyclohexenyl or phenyl groups, X is carbonyl or sulfonyl, and Y is 5-7 atoms-linker, is useful as histone deacetylase inhibitors, particularly for inhibiting cell proliferation.
申请公布号
ZA200305382(B)
申请公布日期
2004.10.11
申请号
ZA20030005382
申请日期
2003.07.11
申请人
F. HOFFMANN-LA ROCHE AG.
发明人
GUY GEORGES;OLAF MUNDIGL;TIM SATTELKAU;ADELBERT GROSSMANN;WOLFGANG VON DER SAAL
