| 发明名称 |
HETEROCYCLIC COMPOUNDS AND METHODS OF USE |
| 摘要 |
The invention relates to compounds of the formulae (I) to (III) wherein the substituents are as defined in the specification. These compounds have kinas e inhibitory activity, such as VEGFR/KDR inhibitory activity. Accordingly, the compounds of the formulae (I) to (III) would be useful in the prevention and treatment of angiogenesis related disorders, ophthalmological conditions, proliferative diseases, inflammatory diseases, and other pathological conditions as described in the specification.
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| 申请公布号 |
CA2518909(A1) |
申请公布日期 |
2004.10.07 |
| 申请号 |
CA20042518909 |
申请日期 |
2004.03.22 |
| 申请人 |
AMGEN INC. |
发明人 |
ELBAUM, DANIEL;POTASHMAN, MICHELE;VAN DER PLAS, SIMON;ASKEW, BENNY C., JR.;GERMAIN, JULIE;HABGOOD, GREGORY J.;KIM, JOSEPH L.;HARMANGE, JEAN-CHRISTOPHE;PATEL, VINOD F.;DI PIETRO, LUCIAN V. |
| 分类号 |
A61P35/00;C07D235/30;C07D401/12;C07D401/14;C07D403/12;C07D413/12;C07D413/14;C07D471/04;C07D487/04;(IPC1-7):C07D401/12;C07D417/12;C07D403/14;C07D417/14;A61K31/418 |
主分类号 |
A61P35/00 |
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