发明名称 COMPOUND HAVING AFFINITY WITH CALCIFIED TISSUE
摘要 A compound excelling in accumulation on calcified tissues, ensuring rapid excretion in the urine and rapid blood clearance, and being useful as a diagnostic agent or therapeutic agent. In particular, a compound having affinity with calcified tissues, represented by the formula (AC)a-MC-(LI)b wherein MC is a mother nucleus being a residue of compound having two or mor e functional groups selected from the group consisting of amino, amido, hydroxyl, thiol, thioether, sulfonyl, phosphonyl, aldehyde, carboxyl, carbonyl, halogen and cyano; AC is a group having affinity with calcified tissues; LI is a ligand capable of bonding with a metal atom; a is an intege r of 1 or greater; and b is 0 or an integer of 1 or greater.
申请公布号 CA2520147(A1) 申请公布日期 2004.10.07
申请号 CA20042520147 申请日期 2004.03.24
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 KURAMI, MIKI;MORISHITA, AKI;ITO, OSAMU;KANAZASHI, NOBUHIKO
分类号 A61K51/04;A61P3/14;A61P9/10;A61P17/00;A61P19/10;A61P29/00;A61P35/00;A61P35/04;C07H15/04;(IPC1-7):C07H15/04;A61K31/703;A61K31/713;A61K51/06 主分类号 A61K51/04
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