| 发明名称 |
BETA AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMETN OR PREVENTION OF DIABETES |
| 摘要 |
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention or diseases in which the dipeptidyl peptidase.IV enzyme Is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. |
| 申请公布号 |
JO2230(B) |
申请公布日期 |
2004.10.07 |
| 申请号 |
JO20020000070 |
申请日期 |
2002.06.30 |
| 申请人 |
MERCK SHARP & DOHME CORPORATION |
发明人 |
SCOTT D EDMONDSON;DOOSEOP KIM;MALCOLM MACCOSS;EMMA R PARMEE;ANN E. WEBER;JINYOU XU;FISHER MICHAEL H |
| 分类号 |
A61K31/498;A61K31/4985;A61K45/00;A61K45/06;A61P1/02;A61P1/04;A61P3/04;A61P3/06;A61P3/10;A61P5/06;A61P5/28;A61P5/50;A61P7/00;A61P9/08;A61P9/10;A61P9/12;A61P13/08;A61P13/12;A61P15/16;A61P19/10;A61P25/00;A61P25/28;A61P27/02;A61P31/18;A61P35/04;A61P37/02;A61P43/00;C07D487/04 |
主分类号 |
A61K31/498 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
