| 发明名称 |
Modified factor VII |
| 摘要 |
The catalytic active site of Factor VII is modified to produce a compound which effectively interrupts the blood coagulation cascade. The modifications render Factor VIIa substantially unable to activate plasma Factors X or IX. The modified Factor VII may be used in conjunction with stents to inhibit coagulation, vascular restenosis, and/or platelet deposition.
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| 申请公布号 |
US2004197370(A1) |
申请公布日期 |
2004.10.07 |
| 申请号 |
US20030738777 |
申请日期 |
2003.12.17 |
| 申请人 |
NOVO NORDISK HEALTH CARE AG |
发明人 |
BERKNER KATHLEEN L.;PETERSEN LARS CHRISTIAN;HART CHARLES E.;HEDNER ULLA;BREGENGAARD CLAUS |
| 分类号 |
A61K38/00;A61K38/16;A61K38/49;C12N9/64;(IPC1-7):A61K38/38;A61F2/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
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| 主权项 |
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