摘要 |
Methods and compositions for modulating interleukin-21 (IL-21)/IL-21 receptor (MU-1) activity using agonists of IL-21 or IL-21 receptor ("IL-21R" or "MU-1"), are disclosed. IL-21/IL-21R agonists can be used by themselves or in combination with 5 anti-inflammatory agents to treat, e.g., ameliorate, symptoms associated with immunological disorders of the nervous system, e.g., multiple sclerosis. |
申请人 |
WYETH;COLLINS, MARY;CHIN, ELAINE, Y.;SENICES, MAYRA;YOUNG, DEBORAH, A. |
发明人 |
COLLINS, MARY;CHIN, ELAINE, Y.;SENICES, MAYRA;YOUNG, DEBORAH, A. |