| 摘要 |
A therapeutic and/or prophylactic drug for osteoarthritis, comprising a derivative of hydroxamic acid, which is represented by the formula (I) (wherein R<1 >represents a halogen atom, C1-8 alkyl, or C1-8 alkyl substituted with -OR<2>, in which R<2 >represents a halogen atom, C1-8 alkyl, benzyl, or C1-8 alkyl substituted with C1-8 alkoxy), or the non-toxic salts with inhibitory effect of matrix metalloproteinase.
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