发明名称 |
Imidazole derivatives modulating the sodium channels |
摘要 |
The invention relates to compounds of general formula (I) where R<1>=an alkyl, cycloalkylalkyl or aralkyl group optionally substituted on the aryl group; R<2>=a phenyl group, or R<2>=an optionally substituted biphenyl group and R<3>=H or alkyl and the pharmaceutically acceptable salts thereof. The above may be used for the production of a medicament for modulating sodium channels and in particular for treatment of pain (for example, neuropathic pain), epilepsy, neurodegenerative conditions and bipolar conditions.
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申请公布号 |
US2004198792(A1) |
申请公布日期 |
2004.10.07 |
申请号 |
US20030480977 |
申请日期 |
2003.12.15 |
申请人 |
BIGG DENNIS;POMMIER JACQUES;LIBERATORE ANNE-MARIE |
发明人 |
BIGG DENNIS;POMMIER JACQUES;LIBERATORE ANNE-MARIE |
分类号 |
C07D233/06;A61K31/00;A61K31/415;A61K31/4164;A61K31/4174;A61P1/12;A61P9/06;A61P25/04;A61P25/08;A61P25/24;A61P25/28;C07D233/10;C07D233/54;(IPC1-7):A61K31/416 |
主分类号 |
C07D233/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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