发明名称 |
BENZYL-PYRIDAZINONS AS REVERSE TRANSCRIPTASE INHIBITORS |
摘要 |
This invention relates to novel pyridazinone derivatives of formula (I) wherein R<1>-R<4>, R<7>, R<8> and X<1> are as defined in the summary and pharmaceutically acceptable salts and solvates thereof, methods to inhibit or modulate Human Immunodeficiency Virus (HIV) reverse transcriptase with compounds of formula (I), pharmaceutical compositions containing of formula (I) admixed with at least one solvent, carrier or excipient and processes to prepare compounds of formula (I). The compounds are useful for treating disorders in which HIV and genetically related viruses are implicated. |
申请公布号 |
WO2004085406(A1) |
申请公布日期 |
2004.10.07 |
申请号 |
WO2004EP02736 |
申请日期 |
2004.03.17 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
DUNN, JAMES, PATRICK;DYMOCK, BRIAN, WILLIAM;MIRZADEGAN, TARANEH;SJOGREN, ERIC, BRIAN;SWALLOW, STEVEN;SWEENEY, ZACHARY, KEVIN |
分类号 |
A61P31/18;C07D237/14;C07D237/22;C07D401/12;C07D405/06;C07D409/06 |
主分类号 |
A61P31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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