发明名称 |
Increased bacterial CoA and acetyl-CoA pools |
摘要 |
Methods of increasing the cellular pool of A-CoA and thus driving the metabolic pathways in the direction of A-CoA containing metabolites by overexpressing rate limiting enzymes in A-CoA synthesis. Methods of increasing intracellular levels of CoA and A-CoA through genetic engineering of bacterial strains in conjunction with supplementation with precursor molecules.
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申请公布号 |
US2004199941(A1) |
申请公布日期 |
2004.10.07 |
申请号 |
US20040808717 |
申请日期 |
2004.03.24 |
申请人 |
RICE UNIVERSITY |
发明人 |
SAN KA-YIU;BENNETT GEORGE NELSON;VADALI RAVISHANKAR V. |
分类号 |
C12N9/02;C12N9/12;C12P1/00;C12P7/62;(IPC1-7):A01H1/00;C12N15/82 |
主分类号 |
C12N9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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