发明名称 TARGETED CD1D MOLECULES
摘要 The invention is directed to a compound comprising one or more CD1d complexes in association with an antibody specific for a cell surface marker. The CD1d complexes comprise a CD1d, a ss2-microglobulin molecule, and may further comprise an antigen bound to the CD1d binding groove. The invention is further directed to methods of inhibiting or stimulating an immune response with the CD1d-antibody compounds, in particular anti-tumor and autoimmunity responses.
申请公布号 WO2004029206(A3) 申请公布日期 2004.10.07
申请号 WO2003US30238 申请日期 2003.09.26
申请人 VACCINEX, INC.;ZAUDERER, MAURICE;ROBERT, BRUNO;DONDA, ALENA;CESSON, VALERIE;MACH, JEAN-PIERRE 发明人 ZAUDERER, MAURICE;ROBERT, BRUNO;DONDA, ALENA;CESSON, VALERIE;MACH, JEAN-PIERRE
分类号 A61K39/00;A61K39/385;A61K39/44;C07K14/74;C07K16/28;C07K16/30 主分类号 A61K39/00
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