NUCLEIC ACID MOLECULES ENCODING SERINE PROTEASE 17, THE ENCODED POLYPEPTIDES AND METHODS BASED THEREON

摘要

Provided herein are polypeptides designated CVSP17 polypeptides that exhibit protease activity as a single chain or as an activated two chain form. Methods using the polypeptides to identify compounds that modulate the protease activity therof are provided. The polypeptides also serve as tumor markers.