发明名称 |
SUGAR-FREE ORAL TRANSMUCOSAL SOLID DOSAGE FORMS AND USES THEREOF |
摘要 |
The present invention is directed to oral solid dosage forms. The solid dosage forms are sugar-free, and comprise a pharmaceutical agent and a suitable pharmaceutically acceptable excipient. Preferably, the solid dosage forms of the present invention are bioequivalent to a sugar-containing solid dosage form. Bioequivalence is preferably obtained by incorporating an ionizing agent, more preferably in the form of a buffer system, into the solid dosage forms, in an amount sufficient to maintain a portion of the pharmaceutical agent, upon dissolution of said composition in saliva, in an ionized state. |
申请公布号 |
WO2004069198(A3) |
申请公布日期 |
2004.10.07 |
申请号 |
WO2004US03055 |
申请日期 |
2004.02.04 |
申请人 |
CEPHALON, INC.;HAGUE, BRIAN;MALAND, LYNN, J. |
发明人 |
HAGUE, BRIAN;MALAND, LYNN, J. |
分类号 |
A61K9/00;A61K9/20;A61K31/4468 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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