发明名称 |
ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION |
摘要 |
The present invention relates to blocking, inhibiting, reduceing, antagonizi ng or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 o r both IL-20 and IL-22 using such antibodies and binding partners.
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申请公布号 |
CA2519089(A1) |
申请公布日期 |
2004.10.07 |
申请号 |
CA20042519089 |
申请日期 |
2004.03.24 |
申请人 |
ZYMOGENETICS, INC. |
发明人 |
SIVAKUMAR, PALLAVUR V.;XU, WENFENG;SIADAK, ANTHONY W.;KINDSVOGEL, WAYNE;DILLON, STACEY R.;CHANDRASEKHER, YASMIN A.;LEHNER, JOYCE M.;MOORE, MARGARET D. |
分类号 |
C07K14/54;C07K14/715;C07K16/24;C07K16/28;(IPC1-7):C07K16/28 |
主分类号 |
C07K14/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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