WÄSSERIGE ZUSAMMENSETZUNG ENTHALTEND AMPHOTERICIN B

摘要

A low toxicity parenteral dimethyl sulfoxide free aqueous compositions containing Amphotericin B are described. The compositions essentially consist of in addition an Amphotericin B, phospholipids and sodium chloride. The compositions are sterilized by autoclaving. The process of making these compositions without the use of solvents for dissolving Amphotericin B have been described. The compositions are indicated for the treatment of invasive fungal infections.