发明名称 |
Method of examining steroid resnponsiveness |
摘要 |
RING6 and HLA-DMB are described herein as genes whose expression levels in mononuclear cells greatly differ between a steroid responder group and a poor steroid responder group in atopic dermatitis patients. Specifically, the expression levels of the RING6 and HLA-DMB genes were demonstrated to be reduced in steroid-responsive patients. Using the expression level of such genes in biological samples as markers of steroid responsiveness, the present invention provides a method of testing for steroid responsiveness and a method of screening for compounds that may be used to improve steroid responsiveness.
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申请公布号 |
US2004197786(A1) |
申请公布日期 |
2004.10.07 |
申请号 |
US20040474079 |
申请日期 |
2004.05.25 |
申请人 |
SUGITA YUJI;HEISHI MASAYUKI;KAGAYA SHINJI;GUNJI SHIGEMICHI;TSUJIMOTO GOZOH |
发明人 |
SUGITA YUJI;HEISHI MASAYUKI;KAGAYA SHINJI;GUNJI SHIGEMICHI;TSUJIMOTO GOZOH |
分类号 |
A01K67/027;A61K31/56;A61K31/7088;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P17/00;A61P29/00;A61P37/08;A61P43/00;C07K14/74;C07K14/78;C07K16/18;C12N15/09;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;(IPC1-7):C12Q1/68 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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地址 |
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