CHEMICAL ENHANCEMENT IN SURFACE ENHANCED RAMAN SCATTERING USING LITHIUM CHLORIDE

摘要

The intensity of the signals from surface enhanced Raman spectroscopy is increased by using lithium chloride (122) as an enhancer to activate a metallic structure (212) used for surface enhanced Raman spectroscopy (116). The increased signal intensity allows surface enhanced Raman spectroscopy to be utilized to detect individual analytes (120) such as nucleotides, for example in DNA sequencing without requiring a dye or radioactive label.